Building the empire: a multi specialist, multi centre pragmatic trial

Does it matter if clinicians recruiting for a trial don't understand what the trial is really about? Qualitative study of surgeons' experiences of participation in a pragmatic multi-centre RCT

BACKGROUND Qualitative methods are increasingly used to study the process of clinical trials and patients understanding of the rationale for trials, randomisation and reasons for taking part or refusing. Patients' understandings are inevitably influenced by the recruiting clinician's understanding of the trial, yet relatively little qualitative work has explored clinicians' perceptions and unde...

Brief Intervention in Type 1 diabetes – Education for Self-efficacy (BITES): Protocol for a randomised control trial to assess biophysical and psychological effectiveness

BACKGROUND Self management is the cornerstone of effective preventive care in diabetes. Educational interventions that provide self-management skills for people with diabetes have been shown to reduce blood glucose concentrations. This in turn has the potential to reduce rates of complications. However, evidence to support type, quantity, setting and mode of delivery of self-management educatio...

A pragmatic multi-centre randomised controlled trial of fluid loading and level of dependency in high-risk surgical patients undergoing major elective surgery: trial protocol

BACKGROUND Patients undergoing major elective or urgent surgery are at high risk of death or significant morbidity. Measures to reduce this morbidity and mortality include pre-operative optimisation and use of higher levels of dependency care after surgery. We propose a pragmatic multi-centre randomised controlled trial of level of dependency and pre-operative fluid therapy in high-risk surgica...

Clinical effectiveness and acceptability of structured group psychoeducation versus optimised unstructured group support for remitted bipolar disorder: a multi-centre pragmatic randomised controlled trial

AI Wall Building in Empire Earth II

Real-Time Strategy games are among the most popular genres of commercial PC games, and also have widely applicable analogs in the field of “Serious Games” such as military simulations, city planning, and other forms of simulation involving multi-agent coordination and an underlying economy. One of the core tasks in playing a traditional Real-Time Strategy game is building a base in an effective...